Burn Multicenter Proposal: Development of an Inhalation Injury Scoring System to Predict Severity of Inhalation Injury
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 9
- 主要终点
- Development of a diagnostic model to predict the severity of inhalation injury
研究概览
简要总结
The goal of this multicenter study is to develop a standardized scoring system for inhalation injury that can be used both to quantify and predict injury severity inhalation injury in adults over 18 years of age. A model will be developed based on clinical, radiographic, bronchoscopic, and biochemical parameters that will predict the severity of inhalation injury with greater than 80% predictive accuracy
详细描述
The goal of this multicenter study is to develop a standardized scoring system for inhalation injury that can be used both to quantify and predict injury severity inhalation injury in adults over 18 years of age. A model will be developed based on clinical, radiographic, bronchoscopic, and biochemical parameters that will predict the severity of inhalation injury with greater than 80% predictive accuracy
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Injury consistent with inhalation of smoke or products of combustion
- •Requires intubation within 24 hours of injury
- •Meets one of the following 4 criteria
- •history of closed space injury
- •carbonaceous sputum
- •elevated carboxyhemoglobin
- •dx of inhalation injury is considered likely by investigator
排除标准
- •≤ 17 years of age
结局指标
主要结局
Development of a diagnostic model to predict the severity of inhalation injury
时间窗: within 48 hours of admission
The development of a diagnostic model to predict the severity of inhalation injury based on demographics, characteristics of injury, bronchoscopy, CT scan, and inflammatory markers.
次要结局
- Impact of inhalation injury(at discharge)