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临床试验/NCT01559337
NCT01559337已完成不适用

Nerve Transfer for Finger Sensory Reconstruction With Dorsal Branch of the Digital Nerve

The Second Hospital of Tangshan1 个研究点 分布在 1 个国家目标入组 17 人开始时间: 2007年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
17
试验地点
1
主要终点
static 2-point discrimination (2PD) test

研究概览

简要总结

A proper digital nerve (PDN) defect causes partial or complete sensory loss of the finger pulp, which results in functional disability.The dorsal branch of the PDN can be transferred for reconstruction of such nerve defects.In this study, the investigators modified the Lesavoy et al' technique and evaluated the efficacy of dorsal sensory branch transfer for PDN defects. For comparison, the investigators collected a consecutive series of 32 patients with finger PDN defects treated using a traditional sural nerve graft from February 2005 to October 2008.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
15 Years 至 50 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Finger PDN defects proximal to the proximal interphalangeal joint
  • Single or two PDN defects
  • PDN defects longer than 1 cm.

排除标准

  • PDN defects less than 1 cm
  • Concomitant injuries to the multiple dorsal sensory branches that preclude their use as nerve donor sites
  • Thumb PDN defects.

结局指标

主要结局

static 2-point discrimination (2PD) test

时间窗: 26 months

At final follow-up, we measured the sensibility of the pulps and the donor sites using the static 2-point discrimination (2PD) test. The test points were at the center of the radial or ulnar portion of the pulp and the donor sites separately. Each area was tested 3 times with a Dellon-Mackinnon discriminator. Two out of 3 correct answers were considered proof of perception before proceeding to another lower value.

次要结局

  • self-administered Cold Intolerance Severity Score (CISS) questionnaire(26 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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