Determinants of Adherence to Post-stroke/Transient Ischemic Attack Secondary Prevention Treatment: Cohort Study in the Rhône
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 633
- 试验地点
- 1
- 主要终点
- Determination of factors influencing compliance with secondary prevention treatment 1 year post a stroke or transient ischemic attack
研究概览
简要总结
The effectiveness of emergency management of acute ischemic stroke has improved considerably in recent years with thrombolysis and more recently thrombectomy. This improvement is accompanied by an increase in the number of stroke survivors. One of the major issues for these ever-increasing survivors is the prevention of recurrence. According to data from the 3 French registries, more than 20% of patients have at least one recurrence. Secondary prevention treatment has demonstrated his efficacy to prevent stroke recurrence.
This evolution justifies identifying factors associated with adherence to secondary prevention treatment, measured at 1 year post-stroke / transient ischemic attack (TIA), in patients included in the STROKE 69 cohort.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Consecutive patients treated for a stroke suspicion at the acute phase,
- •with symptom onset (the last time the patient was seen without deficit ) less than 24 hours,
- •Managed by the Rhône's emergency medical help service (SAMU), in one of the emergency unit or stroke unit of the Rhône area
- •Having given their written consent for the extraction of their healthcare consumption data from the Health Insurance databases
排除标准
- •Hemorrhagic stroke,
- •Patient institutionalized in the year following the stroke / transient ischemic attack,
- •Patient unable to take treatment alone.
结局指标
主要结局
Determination of factors influencing compliance with secondary prevention treatment 1 year post a stroke or transient ischemic attack
时间窗: 1 year post a stroke or transient ischemic attack
A phone call will be made to patients 1 year post a stroke or transient ischemic attack. The following determinants will be studied in the 5 dimensions defined by World Health Organization: 1. Socio-economic: level of education, profession, health insurance 2. Patient and family-social environment: age, sex, marital status, lifestyle, level of patient support in the management of their treatment, representation of the disease and beliefs about medication 3. Care pathway: management of stroke / TIA in emergency or neurovascular unit, admission to rehabilitation unit, medical consumption and therapeutics acts in the year following stroke / TIA 4. Pathology: TIA or ischemic stroke, duration of hospitalization in acute phase and type of hospital, history of stroke or TIA, disability and autonomy, fatigue, anxiety and depression, comorbidities 5. Treatments: therapeutic class and number of treatments / polymedication.
Compliance to secondary prevention treatment 1 year post a stroke or transient ischemic attack
时间窗: 1 year post a stroke or transient ischemic attack
The overall medication possession ratio is the average of the medication possession ratio calculated for each therapeutic class (antiplatelet agents, anticoagulants, antihypertensives, hypolipidemic agents and oral antidiabetics). The medication possession ratio will be calculated from dispensing data from regional health insurance database and prescription data from the STROKE 69 study. For each patient, a medication possession ratio (CMA7 index) will be obtained by the ratio of the quantity of medication units dispensed to the quantity of medication units prescribed.
次要结局
未报告次要终点