NCT03039829已完成不适用
Short-Term Safety and Dose Effects of Different Forms of Creatine
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 主要终点
- Measuring the heart rate response to creatine nitrate ingestion
研究概览
简要总结
This study will aim to determine whether ingesting creatine nitrate (CrN) at higher doses will differentially affect hemodynamic variables compared to a placebo.
详细描述
This study will examine the short-term (7 day) characteristics of ingesting creatine nitrate (CrN) compared to placebo on Chem-15 blood safety, heart rate, blood pressure, heart rate and blood pressure reactivity and self-reported side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Health Services Research
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Apparently healthy
- •At least 6 months immediate prior history of resistance training including bench press and leg press or squat
排除标准
- •A history of treatment for metabolic disease (i.e., diabetes), hypertension, hypotension, thyroid disease, arrhythmias and/or cardiovascular disease
- •Use of prescription medication (birth control is allowed)
- •Pregnant or nursing or plan to become pregnant during the next month
- •Creatine or nitrate use in the last eight weeks
- •History of smoking
- •History of drinking (i.e., 12 drinks per week or more)
- •Use of nonsteroidal anti-inflammatory drugs (NSAIDs) including ibuprofen (Advil, Motrin, Nuprin, etc.), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene)
结局指标
主要结局
Measuring the heart rate response to creatine nitrate ingestion
时间窗: 7 days
Measuring the blood pressure response to creatine nitrate ingestion
时间窗: 7 days
次要结局
- Measuring a blood chemistry panel 15 response to creatine nitrate ingestion(7 days)
- Measuring the one Repetition Maximum (1 RM) muscle strength response to creatine nitrate ingestion(7 days)
- Measuring the repetitions to failure muscle endurance response to creatine nitrate ingestion(7 days)
- Measuring self-reported side effects of creatine nitrate ingestion(7 days)
研究者
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