CTRI/2019/03/017955尚未招募不适用
Comparison of effectiveness of trihexyphenidyl and levodopa on motor symptoms in Parkinson’s disease
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Decrease in UPDRS motor scores after the treatment
研究概览
简要总结
There are very few studies assessingthe effectiveness of trihexyphenidyl inimproving motor symptoms in PD.Studies comparing effectiveness of trihexyphenidyl and levodopa in PDpatients are also very rare.We plan to evaluate 30 patients with Parkinson’s disease and objectively assess the response of their motor features to levodopa and trihexyphenidyl respectively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 30.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Parkinson’s disease patients (fulfilling MDS clinical diagnostic criteria for PD) (who are currently taking or had taken trihexyphenidyl in the past).
排除标准
- •1.Patients with cognitive and behavioral disturbances.
- •2.Patients with history of urinary disturbances and benign hyperplasia of prostate.
- •3.Patients with angle closure glaucoma.
- •4.Patients with h/o cardiac illness 5.Patients with h/o postural hypotension.
- •6.Lack of consent.
结局指标
主要结局
Decrease in UPDRS motor scores after the treatment
时间窗: Baseline, after 1 hour of levodopa tablets, after 48 hours, after 30 minutes, after 60 minutes, after 90 minutes, after 120 minutes
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
Effectiveness of treatment in Parkinsons diseaseCTRI/2019/03/017955Department of Neurology
已完成
不适用
Oral drugs for dystonia in children with cerebral palsyCTRI/2020/07/026504All India Institute of Medical Sciences
尚未招募
1 期
Effectiveness of the drug Trihexyphenidyl for abnormal movements in children with Cerebral PalsyCTRI/2018/01/011571Maulana Azad Medical College
尚未招募
1/2 期
Effectiveness of the drug Trihexyphenidyl for abnormal movements in children with Cerebral PalsyCTRI/2018/01/011571Maulana Azad Medical College30
招募中
不适用
CD triheptanoin Clinical TrialsjRCTs0312307556