JPRN-UMIN000004962已完成2 期
Study of efficacy and tolerability of combination therapy with palonosetron and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting in patients with cervical cancer. - Study of efficacy and tolerability of combination therapy with palonosetron and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting in patients with cervical cancer.
Kyoto University Graduate School of Medicine0 个研究点目标入组 40 人开始时间: 2011年2月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- Female
入选标准
- 未提供
排除标准
- •# They had serious complication. (intestinal paralysis, lung fibrosis, diabetes mellitus, heart failure, myocardial infarction, angina pectoris, renal failure, psychiatric disorder, cerebrovascular accident, active gastric ulcer, active duodenal ulcer) # No known CNS metastasis # Patients who has a convulsive disorders that need anticonvulsants therapy # They had ascites or pleural effusion needs paracentesis treatment # Patients with obstruction of gastrointestinal tract,for example gastric outlet or ileus # Patients with vomiting or nausea (>= Grade2) # Hypersensitivity or severe drug allergy for Aloxi or other 5-HT3RA # Hypersensitivity or severe drug allergy for dexamethasone # Pregnant, breastfeeding or expecting woman # Patients judged inappropriate for this study by physicians
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