ISRCTN31557558已完成不适用

A pilot multi-centre randomised controlled trial of sequential treatment with Mitoxantrone and Glatiramer Acetate vs Interferon Beta-1a in early active relapsing remitting Multiple Sclerosis

Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)0 个研究点目标入组 0 人开始时间: 2005年9月30日最近更新: 2015年1月13日

试验速览

暂无简介。

•1. Definite MS as determined by the McDonald criteria (Ann Neurol, July 2001) with a relapsing remitting disease course.
•2. Aged 18 to 55.
•3. 2 relapses in the past 2 years (this is part of the ABN guidelines to use GA and Interferon).
•4. EDSS 0 - 5.5 (able to walk at least 100m without aid).
•5. Disease duration less than 5 years from onset (if used later in the disease may not prevent progression).
•6. At least 3 of the following: patients with three or more attacks in the first two years of disease; motor involvement in early attacks (weakness/ataxia); incomplete recovery from early attacks (EDSS >1.5); 10 or more T2 weighted MRI brain lesions (these 4 items are markers of increased risk of early disability).

发起方

Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)