Maternal-fetal Outcomes of Genital Blood Loss Beyond 18 Weeks of Pregnancy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Rate of hospitalization for genital blood loss
研究概览
简要总结
The primary objective is to assess in terms of frequency the adverse outcomes (premature birth, maternal-fetal haemorrhage, maternal fetal-neonatal death) of pregnancies of women attending the obstetric-gynaecological emergency department for genital bleeding beyond the 18th week of pregnancy.
详细描述
The investigators decided to conduct this study because it is important on the one hand to carefully evaluate maternal-fetal outcomes in pregnancies characterised by genital bleeding in the second and third trimesters and on the other hand to evaluate the sonographic diagnostic capacity for identifying the aetiology of these genital bleedings, in order to understand whether the possibility of identifying a specific cause of the bleeding has also improved over time as sonographic techniques have improved. This could then allow management and subsequent obstetrical controls to be adapted in a more accurate and indivudualised manner.
For the purpose of this study, no study-specific visits are planned. Data collected during pregnancy and delivery data for patients who gave birth at our centre will be analysed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnancy beyond 18 weeks gestational age complicated by genital bleeding;
- •Age of the patient ≥18 years;
- •Delivery at the O.U. of Obstetrics and Prenatal Age Medicine
排除标准
- 未提供
结局指标
主要结局
Rate of hospitalization for genital blood loss
时间窗: After the 18th week of pregnancy
Percentage of spontaneous deliveries, operative vaginal, cesarean sections (elective, urgent, emergent)
时间窗: After delivery, up to 24 weeks
Percentage of preterm births
时间窗: After delivery, up to 24 weeks
Frequency of antihemorrhagic therapy and maternal transfusions
时间窗: Intra-partum and post-partum, up to 24 weeks
Frequency of live births, average APGAR, average pH of umbilical artery or vein, average neonatal weight
时间窗: After delivery, up to 24 weeks
Average length of hospitalization in hours
时间窗: During Hospitalization, up to 24 weeks
次要结局
- Frequency of finding abnormal ultrasound findings corresponding to the etiology of bleeding(During the obstetric ultrasound performed at the time of admission)