The Effect of Gabapentin Pretreatment on Hyperalgesia in Elderly Patients Undergoing Staged Bilateral Cataract Operations
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Pain perception
研究概览
简要总结
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
详细描述
It has been reported that patients with bilateral cataract complained more pain and discomfort during the second consecutive eye surgery compared to the first eye surgery.
Gabapentin is an anticonvulsant drug, which has been extended the use to perioperative analgesia, and anxiolysis.
Therefore, the investigators conducted this randomized, controlled study to evaluate the effects of gabapentin premedication on patients' subjective sensations, including intraoperative anxiety, perceptions of pain, and light sensitivity, in the second cataract operations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients aged over 60 years, who undergoing staged bilateral cataract operations under monitored anesthesia care
- •ASA physical status of I, II, and III
排除标准
- •undergoing other eye operations together besides cataract operation
- •patients with creatinin clearance lower than 30ml/min
- •patients with CNS inhibitors medication
- •patients with previous gabapentin medication
- •pregnancy
研究组 & 干预措施
Gabapentin
Gabapentin premedication group
干预措施: Gabapentin (Drug)
结局指标
主要结局
Pain perception
时间窗: during the operation
intraoperative pain perception evaluated by VAS in first and second cataract surgery
次要结局
未报告次要终点
研究者
Jeong-Hwa Seo
Professor
Seoul National University Hospital