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临床试验/NCT01801787
NCT01801787已完成不适用

The Mechanism of Non-invasive Brain Stimulation for Therapy of Chronic Auditory Verbal Hallucinations in Schizophrenia

Charite University, Berlin, Germany3 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2013年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
3
主要终点
Change of Auditory Hallucination Rating Scale score

研究概览

简要总结

The current study investigates the basic principles that underlie the efficacy of transcranial direct current stimulation for chronic auditory verbal hallucinations in schizophrenia in a multimodal design.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Triple (Participant, Care Provider, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • diagnosis of schizophrenia
  • chronic auditory verbal hallucinations
  • right-handed

排除标准

  • drug abuse other than nicotine
  • severe cognitive deficits
  • severe medical conditions
  • severe neurological disorders
  • severe microangiopathy
  • history of electroconvulsive therapy
  • pregnancy or lactation

结局指标

主要结局

Change of Auditory Hallucination Rating Scale score

时间窗: baseline; 3 days after intervention; 3 months after intervention

Auditory Hallucination Rating Scale score will be assessed at baseline; changes thereof at 3 days after intervention and 3 months after intervention are primary outcome measures

次要结局

  • Positive And Negative Syndrome Scale(baseline; 3 days after intervention; 3 months after intervention)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Andres Neuhaus, MD

M.D.

Charite University, Berlin, Germany

研究点 (3)

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