Randomized Controlled Trial: Does First Oral Intake After Emergence From Anesthesia Predict the Incidence of Post-operative Vomiting in Children?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 183
- 试验地点
- 2
- 主要终点
- Post-operative Vomiting
研究概览
简要总结
Second only to pain, nausea and vomiting are the most uncomfortable complications of surgery and anesthesia. Unfortunately, our best defense against post-operative nausea and vomiting, a medicine called ondansetron (Zofran), is in dire national shortage. Consequently, non-pharmacological methods of prevention and treatment for post-operative nausea and vomiting have increased import. Following emergence from general anesthesia, children often request food and drink. There have been no studies to date that definitively determine the optimal first food or drink choice for these children. This study proposes to randomize children to either water or juice first intake following surgery. The investigators expect to find that children who consume glucose are less likely to vomit than those who first receive water.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- Double (Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 2 Years 至 18 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Dental surgery
- •Tonsillectomy and adenoidectomy
- •Strabismus surgery
排除标准
- •Patient refusal
- •Parent refusal
- •Allergy / contraindication to ondansetron
- •Prone to vomiting
- •Inpatient
- •Preoperative anxiolysis with ketamine
- •Recovery location other than PACU
- •Nil per os at baseline
- •Presence of enteric tube
- •Contraindication to any part of the study protocol
结局指标
主要结局
Post-operative Vomiting
时间窗: 24 hr post-op
Patients will be assessed for vomiting upon entry to PACU until 24 hours post-operatively.
次要结局
未报告次要终点
