Efficacy of Single Level Versus Bilevel Serratus Anterior Plane Block With Dexmedetomidine During Breast Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 172
- 试验地点
- 2
- 主要终点
- First time to receive analgesia
研究概览
简要总结
This study aims to compare single level serratus block versus bilevel serratus block with and without dexmedetomidine in cancer patients undergoing modified radical mastectomy for breast cancer regarding pain control and possible side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •patients scheduled for modified radical mastectomy,
- •Age 18-65 years,
排除标准
- •patient refusal,
- •coagulation defects,
- •abnormal kidney or liver functions,
- •local infection at site of injection.
研究组 & 干预措施
Single level serratus anterior plane block with dexmedetomidine
the allocated patients will receive single injection serratus anterior plane block at the level of third rib with local anesthetics and dexmedetomidine
干预措施: Single level serratus anterior plane block with dexmedetomidine (Procedure)
Bilevel serratus anterior plane block
the allocated patients will receive injection serratus anterior plane block at 2 levels, the level of third rib and the level of the fifth rib with local anesthetics only
干预措施: Bilevel serratus anterior plane block (Procedure)
Bilevel serratus anterior plane block with dexmedetomidine
the allocated patients will receive injection serratus anterior plane block at 2 levels, the level of third rib and the level of the fifth rib with local anesthetics and dexmedetomidine
干预措施: Bilevel serratus anterior plane block with dexmedetomidine (Procedure)
Single level serratus anterior plane block
the allocated patients will receive single injection serratus anterior plane block at the level of third rib with local anesthetics only
干预措施: Single level serratus anterior plane block (Procedure)
结局指标
主要结局
First time to receive analgesia
时间窗: First 24 hours postoperatively
first time to receive morphine analgesia in hours
Total analgesic requisite
时间窗: First 24 hours postoperatively
total amount of morphine consumption in the first 24 hours postoperatively in mg
次要结局
- Pain scores(First 24 hours postoperatively)
- Side effects(First 24 hours postoperatively)
- Perioperative heart rate values(First 24 hours)
- Mean arterial blood pressure(First 24 hours)
研究者
Walaa Youssef Elsabeeny
Assistant professor of Anesthesia and Pain management
National Cancer Institute, Egypt