Cytopathologic Margin Evaluation in Patients Undergoing Pancreatic Cancer Resection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Local recurrence at the site of resection
研究概览
简要总结
This study is being done to investigate another way of evaluating margin status after pancreatectomy by using cytopathology (slide interpretation) as compared to the traditional method of surgical pathology
详细描述
PRIMARY OBJECTIVES:
I. To compare margin status on final pathology with margin status from cytopathologic evaluation.
OUTLINE:
Patients undergo cytopathologic sample collection during pancreatic resection during which slides are gently pressed against the cut edge of the pancreas, the surgical bed, and along the superior mesenteric artery, and finally against the tumor itself.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing pancreatic resection for a presumed, although not necessarily biopsy-proven pancreatic malignancy,
- •ages 18 years to 80 years old
排除标准
- •Pregnant women
研究组 & 干预措施
Diagnostic (cytopathologic evaluation)
Patients undergo cytopathologic sample collection during pancreatic resection during which slides are gently pressed against the cut edge of the pancreas, the surgical bed, and along the superior mesenteric artery, and finally against the tumor itself.
干预措施: cytology specimen collection procedure (Other)
结局指标
主要结局
Local recurrence at the site of resection
时间窗: up to 2 years
Will be evaluated in a Cox proportion hazards regression model. The prognostic ability of the histological reporting of the specimen margin as well as the cytopathological reporting of the specimen and in situ margins will be evaluated.
次要结局
未报告次要终点