The Analgesic Efficacy of the Ultrasound Guided Transversus Abdominis Plane Block After Inguinal Hernia Repair With a Mesh.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 59
- 试验地点
- 1
- 主要终点
- Pain scores at rest and with movement using the numerical rating scale (NRS)
研究概览
简要总结
This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients undergoing unilateral inguinal hernia repair with a mesh under general anaesthesia, and how the efficiency of early postoperative analgesia achieved correlates with the risk of developing a chronic pain state, a not uncommon condition after this type of surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-III patients undergoing inguinal hernia repair with a mesh
- •age between 18 and 75 years old
- •ability to read and write greek
排除标准
- •Inability to consent to the study
- •BMI >40kg/m2
- •Skin infection at the puncture site
- •Contraindication to mono-amide local anaesthetics, paracetamol, NSAID's (parecoxib)
- •Preoperative use of opioids or NSAID's for chronic pain conditions
研究组 & 干预措施
Transversus abdominis plane block with 20 ml ropivacaine 0,75%
Transversus abdominis plane block with 20 ml ropivacaine 0,75%
干预措施: Transversus abdominis plane block (Procedure)
Transversus abdominis plane block with 20 ml saline
Transversus abdominis plane block with 20 ml saline
干预措施: Transversus abdominis plane block (Procedure)
结局指标
主要结局
Pain scores at rest and with movement using the numerical rating scale (NRS)
时间窗: 3, 6 and 24 hours postoperatively
次要结局
- Incidence of chronic pain(6 months after surgery)
研究者
Papacharalampous Panagiota
Anesthesiologist
Aretaieion University Hospital