Study on intervention effect and intestinal environment of 'phlegm dampness constitution NAFLD' population based on metagenomics

The Second Affiliated Hospital of Shandong University of traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•1. Patients aged 20-50 years old;
•2. Patients who meet the criteria of mild constitution and phlegm dampness constitution respectively;
•3. Patients who have lived in Jinan for more than one year and have not taken antibiotics and other drugs within one month;
•4. Patients who have no major disease and have the ability to cooperate with the completion of this trial;
•5. Phlegm dampness constitution NAFLD population should meet the following three conditions at the same time:
•(1) There was no history of alcohol drinking or the equivalent alcohol consumption was less than 140g / week (female less than 70g / week);
•(2) Except viral hepatitis, drug-induced liver disease, total parenteral nutrition, hepatolenticular degeneration, autoimmune liver disease and other specific diseases that can lead to fatty liver;
•(3) The histological changes of liver biopsy were consistent with the pathological diagnostic criteria of fatty liver disease. In view of the difficulty in obtaining liver histological diagnosis, NAFLD was defined as:
•No history of drinking;
•The imaging findings of the liver were consistent with the diagnostic criteria of diffuse fatty liver, and there was no other reason to explain.

•1. Patients taking various drugs or receiving other treatments;
•2. Patients with other diseases such as severe hypertension and organic heart disease;
•3. Pregnant, menstrual and lactating women.

发起方

The Second Affiliated Hospital of Shandong University of traditional Chinese Medicine