跳至主要内容
临床试验/NCT04929574
NCT04929574招募中不适用

Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram

Nanfang Hospital, Southern Medical University1 个研究点 分布在 1 个国家目标入组 1,200 人开始时间: 2021年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
1,200
试验地点
1
主要终点
Echocardiogram

研究概览

简要总结

Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of cardiomyocytes and can also lead to myocarditis, pericarditis, and arrhythmias. The severity of cardiac dysfunction depends on the amount of iron deposited in the myocardium.Echocardiogram is used as noninvasive method to observe heart status. The objective of this study is to evaluate the heart status in patients of Beta Thalassemia from southern China.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Diagnosed with beta-thalassemia

排除标准

  • Iron deficiency anemia

结局指标

主要结局

Echocardiogram

时间窗: 3 years

Evaluation of heart function in beta thalassemia patients by left ventricular fraction shortening

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验