The Effect of Estrogen Levels on Cooperative and Competitive Decision Making and Risk Preferences
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Change of E2 [mg/l]
研究概览
简要总结
This study observes the effects of female cycle hormones on cooperation, competitiveness and risk preferences under experimental conditions. Especially, the causal effect of estradiol is isolated.
详细描述
Behavioural theories assume that, as a result of natural selection, women undergo a brief, unconscious change in some psychological aspects during ovulation. This short-term change, "ovulatory shift", is assumed to aim to increase the probability of successful reproduction in the decisive days of the female cycle. Amongst others, it is assumed that women behave particularly uncooperatively and particularly competitively towards other women during the fertile days. Though, empirical evidence is ambiguous.
The effect on risk preferences is unclear. Theory generally assumes that female risk aversion increases in the fertile days. However, empirical studies find partly positive and partly negative correlations.
Within the scope of this study, estradiol levels which are collected in the clinical treatment of patients in the Clinic for Gynaecological Endocrinology and Reproductive Medicine are to be linked with the behavioural economic measures of cooperation, competitiveness, and risk preferences, which are collected using questionnaires or a computer-based decision task.
The aim of the research project is to quasi-experimentally isolate the effect of estradiol on competitiveness, cooperation and risk preferences of women.
No study known to us has ever been able to realize a comparable quasi-experimental design which is necessary to isolate the causal effect of estradiol on different behavioural measures.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patient in fertility treatment according to Long GnRH Agonist Protocol
- •18 years and older
- •written declaration of consent
- •persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
- •understanding of the German language (written and spoken)
- •Control group
- •18 Years and older
- •written declaration of consent
- •persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
- •understanding of the German language (written and spoken)
排除标准
- •pregnant and breastfeeding women
- •persons who are accommodated in an institution on official or court order
- •persons in a dependent or employment relationship with the auditor
- •simultaneous participation in another clinical trial
- •Control group
- •persons who are accommodated in an institution on official or court order
- •persons in a dependent or employment relationship with the auditor
- •simultaneous participation in another clinical trial
结局指标
主要结局
Change of E2 [mg/l]
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of estradiol (E2) in mg/l
Change of LH [mg/l]
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of the luteinizing hormone (LH) in mg/l
Change of Cooperation 1
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the Social Value Orientation German A (Murphy et al. 2011)
Change of Prog [mg/l]
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of progesterone (Prog) in mg/l
Change of Competitiveness 1
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
Change of Competitiveness 2
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the Willingness to compete measure based on Niederle \& Vesterlund (2007)
Change of Risk Preference 2
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the Risk aversion measure by Holt \& Laury (2002)
Change of Risk Preference 1
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the SOEP Risk Attitude (DIW Berlin)
Change of Cooperation 2
时间窗: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
次要结局
未报告次要终点
研究者
Frederik Graff
Assistant Professor
RWTH Aachen University