Relationship of Retinal and Visual Cortex Structure and Visual Acuity After Congenital Cataract Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Macular thickness
研究概览
简要总结
To evaluate the influence of the visual acuity after congenital surgery on the retinal and visual cortex structure.
详细描述
According to the visual acuity after congenital cataract surgery, 30 patients are divided into 3 groups.SD-OCT and MRI were used to measure the parameters of the retina and the visual cortex, to compare the differences between different groups, and to analyze the relationship between the structure of the retina and the visual cortex and visual acuity.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 4 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age of 4-60 years
- •Congenital cataract surgery is planned
- •The operation was successful without any complications
- •Can cooperate well with OCT and MRI examinations
排除标准
- •Intraoperative and postoperative complications include glaucoma, retinal, corneal, or refractive medium diseases
- •Behavioral, cognitive impairment
- •Developmental delay
结局指标
主要结局
Macular thickness
时间窗: 2021.12.30
Scan the 3.0mm diameter ETDRS ring area in the macular area with SD-OCT.
Subfoveal choroidal thickness
时间窗: 2021.12.30
Scan the Subfoveal choroid in enhanced scan mode with SD-OCT.
Retinal nerve fiber layer thickness
时间窗: 2021.12.30
Scan concentric circles with a length of 3.4mm and a diameter ranging from 2.5mm to 4.0mm in 12 directions centered on the optic disc with SD-OCT.
The volume of the lateral geniculate body
时间窗: 2021.12.30
Measure the volume of the lateral geniculate body by T1 phase scan of MRI
The volume of the brodmann 17,18,19 area
时间窗: 2021.12.30
Masure the volume of the brodmann 17,18,19 area by T1 phase scan of MRI
The FA of the white matter fiber bundle
时间窗: 2021.12.30
Measure the Fraction Anisotropy of the white matter fiber bundle related to visual signal transduction by DWI scan of MRI
次要结局
未报告次要终点
研究者
Yune Zhao
Vice president of Eye Hospital of Wenzhou Medical University
Wenzhou Medical University