Neuromodulation and Its Effects on Muscle Activity and Fatigue
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Perception of effort
研究概览
简要总结
In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation. Healthy individuals will participate in one familiarization followed by up to 6 experimental sessions. Fatigability and motor function will be assessed in each test session.
详细描述
This project will investigate the potential impact of an electrical current of low intensity, and applied non-invasively, on the signals that drive muscle contractions. Individuals will receive distinct types of stimulation that vary depending on the direction on the current (anodal vs cathodal) and placement of the electrodes. These conditions will be compared to a sham stimulation. The test session will be randomized in a double blind fashion, which indicates that neither participants or investigators will know the type of stimulation. Motor function and the muscle electrical activity will be quantified during each test session.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy individuals between 18 and 50 years old
排除标准
- •Metal implants or joint replacement. Presence of neuromuscular disease. Skin hypersensitivity.
研究组 & 干预措施
Men
Individuals will participate in 1 familiarization and up to 6 test sessions
干预措施: electrical stimulation (Behavioral)
Women
Individuals will participate in 1 familiarization and up to 6 test sessions
干预措施: electrical stimulation (Behavioral)
结局指标
主要结局
Perception of effort
时间窗: Each session will take approximately 2 hours (total of 4 test sessions)
Change in perceived effort will be evaluated with visual analogue scales
Force
时间窗: Each session will take approximately 2 hours (total of 4 test sessions)
Change in force will be evaluated with a device during each test session
Muscle activation
时间窗: Each session will take approximately 2 hours (total of 4 test sessions)
Electromyography will be used to quantify muscle activation
次要结局
未报告次要终点