Clinical Evaluation of the Treatment of Multiple Gingival Recessions with Connective Tissue Graft or Concentrated Growth Factor Membrane Using Tunnel Technique: a Randomized Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Complete root coverage
研究概览
简要总结
This randomized controlled clinical study aimed to evaluate the success of the combination of tunnel technique and concentrated growth factor membrane for root coverage in treating multiple gingival recessions and compare with the gold standard connective tissue graft.
详细描述
The study included 108 defects in 40 patients with Miller Class I and II gingival recession. Gingival recession defects were randomly divided into two groups. Tunnel technique + connective tissue graft was applied to 20 patients in the control group (51 defects) and tunnel technique + concentrated growth factor membrane was applied to 20 patients in the test group (57 defects). The results at baseline and 6 months were evaluated for the following clinical parameters: Mean root coverage, complete root coverage, probing depth, clinical attachment level, gingival recession depth, gingival recession width, keratinized tissue width and gingival thickness.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥18 years
- •periodontally and systemically healthy
- •presence of Miller I or II class gingival recession defect in at least two teeth on the buccal aspect of incisors, canine and premolar teeth (≥ 2 mm in depth)
- •gingival thickness ≥ 0.8 mm 2 mm apical to the gingival margin
- •presence of identifiable cementoenamel junction (CEJ) (step ≤1 mm at the CEJ level and/or presence of a root irregularity/abrasion with identifiable CEJ was accepted
- •full-mouth plaque score (FMPS) ≤20%.
排除标准
- •contraindications for surgical periodontal treatment
- •presence of recession defects associated caries, restoration and furcation problems
- •use of systemic antibiotics for any reason in the last 3 months.
结局指标
主要结局
Complete root coverage
时间窗: Six months
Change from baseline in percentage of complete root coverage at 6th months.
次要结局
- Mean root coverage(Six months)
- Probing depth(Six months)
- Clinical attachment level(Six months)
- Gingival recession depth(Six months)
- Gingival recession width(Six months)
- Keratinized tissue width(Six months)
- Gingival thickness(Six months)
研究者
Umut BALLI
Associate professor
Bulent Ecevit University