EUCTR2017-000927-29-NL
进行中（未招募）
1 期
Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, open-label, single-arm, phase II study (CRC-PIPAC) - CRC-PIPAC
概览
- 阶段
- 1 期
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- Catharina Ziekenhuis
- 入组人数
- 20
- 状态
- 进行中（未招募）
- 最后更新
- 7年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Eligible patients are adults who have:
- •? a World Health Organisation (WHO) performance status of \=1 and life expectancy \>3 months;
- •? histological or cytological proof of PM of a colorectal or appendiceal carcinoma;
- •? unresectable disease determined by abdominal computed tomography (CT) and a diagnos\-tic laparoscopy or laparotomy; .
- •? adequate organ functions (haemoglobin \=5\.0 mmol/L, neutrophils \=1\.5 x 109/L, platelets \=100 x 109/L, serum creatinine \<1\.5 x ULN, creatinine clearance \=30 ml/min, and liver trans\-aminsases \<5 x ULN);
- •? no symptoms of gastrointestinal obstruction;
- •? no radiological evidence of systemic metastases;
- •? no contraindications for oxaliplatin or 5\-fluorouracil/leucovorin;
- •? no contraindications for a laparoscopy; ? no previous PIPAC\-procedures;
- •? written informed consent.
排除标准
- •See inclusion criteria
结局指标
主要结局
未指定
相似试验
已完成
不适用
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已完成
2 期
Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, open-label, single-arm, phase II study (CRC-PIPAC)Unresectable isolated colorectal peritoneal metastasesinoperable peritoneal metastases of large bowel cancer100179901002747610017998NL-OMON49271Catharina-ziekenhuis20
已完成
2 期
PIPAC for peritoneal metastases of colorectal cancerIsolated unresectable colorectal peritoneal metastasesCancerISRCTN89947480Catharina Hospital20
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不适用
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