Alternative Home Training Possibilities for Glaucoma Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 4
- 主要终点
- Visual field size determined by perimetry measurements
研究概览
简要总结
The aim of the trial is to investigate the possibilities of improving visual impairments with eye training exercises (eye-yoga) in a total of 40 patients with glaucoma who have not previously been treated within a similar training program. 20 patients will be instructed how to do eye yoga to be performed dails for 4 weeks (max 30 min/day). As a control group of 20 patients will be instructed to read for 30 min/day for 4 weeks.
The following outcome measures will be investigated: High Resolution Perimetry, Humphrey Perimetry, Visual Acuity Test, Contrast Sensitivity Test, Microsaccades measurements, Intraocular Pressure Measurement, Electroencephalogram (EEG), Blood Pressure and Pulse Measurement and Dynamic Vessel Analysis (DVA - the blood supply in the eye (especially vascular dysregulation) .
Furthermore, factors that could influence response variability and the effectiveness of treatment will be analysed: (i) the role of mental stress (or stress resilience) and (ii) the influence of personality traits and quality of life.
The study is intended to further validate this home training program (eye yoga) for the treatment of visual impairment in glaucoma.
详细描述
The aim of eye yoga is to improve microsaccade impairments in patient with primary open angle glaucoma. We will study how this affects visual performance and the physiology of the eye and brain
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical diagnosis of glaucoma
- •residual vision
- •the duration of the disease must be at least 6 months old
- •the visual field defect must be stable
排除标准
- •autoimmune diseases in the acute stage
- •neurological and mental diseases
- •diabetic retinopathy
- •addictions
- •hypertension (maximum 160/100 mmHg)
- •retinitis pigmentosa-
- •pathological nystagmus
- •non-distant tumors or recurrent tumors
- •photosensitivity
- •pregnancy
结局指标
主要结局
Visual field size determined by perimetry measurements
时间窗: 4 weeks
Changes of the visual field's size, evaluated by static perimetry and high resolution perimetry measurements
Microsaccade measurements
时间窗: 4 weeks
Changes in the deviation of eye movements when visual targets are followed, using a computerized test
次要结局
- EEG connectivities(4 weeks)
- Blood circulation in the eye(4 weeks)
研究者
Bernhard A. Sabel
Head of Institute, Professor
University of Magdeburg