Staging Classification of Severe Tricuspid Regurgitation Using Novel Cardiac Imaging Techniques
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Incidence of Severity of tricuspid regurgitation by cardiac magnetic resonance imaging
研究概览
简要总结
The purpose of this research is to assess the severity of tricuspid regurgitation (a disorder in which the tricuspid valve in the heart does not close tight enough) using cardiac magnetic resonance imaging (MRI).
详细描述
40 patients with moderate or more TR on echocardiography will undergo CMR/MRE with contrast to assess TR severity, and the associated extra-valvular cardiac and liver abnormalities as shown in the flow diagram below. Patients will continue their clinical management by their primary physicians as per the standards of care. 1-year follow up will be conducted via phone to inquire about patient's vital status (dead/alive), symptoms and hospitalizations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Moderate or more tricuspid regurgitation
排除标准
- •Prior tricuspid valve prosthesis
- •Pacemaker/defibrillator that would impede MRI imaging
- •Planned tricuspid valve surgery
- •Primary liver pathology
研究组 & 干预措施
Moderate or severe tricuspid regurgitation
40 patients with moderate or more TR on echocardiography will undergo CMR/MRE with contrast to assess TR severity, and the associated extra-valvular cardiac and liver abnormalities. Patients will continue their clinical management by their primary physicians as per the standards of care. 1-year follow up will be conducted via phone to inquire about patient's vital status (dead/alive), symptoms and hospitalizations.
干预措施: Cardiac Magnetic Resonance (Diagnostic Test)
结局指标
主要结局
Incidence of Severity of tricuspid regurgitation by cardiac magnetic resonance imaging
时间窗: 1 year
Incidence of severity of TR by CMR as compared with current gold standard (TTE)
次要结局
- Correlation between severity of Tricuspid regurgitation by cardiac magnetic resonance imaging vs. elastography(1 year)
研究者
Mohamad Adnan Alkhouli
Professor of Medicine
Mayo Clinic