Hypotension Prediction Index in Postoperative Surgical Patients in the Post-anesthetic Recovery Room - a Feasibility Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Incidence of intraoperative hypotension
研究概览
简要总结
PACU-HPI study evaluates the use of a hemodynamic monitor in the post-anesthetic recovery room on patients undergoing colorectal, hepatobiliary, and vascular surgery, to determine the feasibility of recruiting this surgical population.
详细描述
Postoperative vascular complications, including myocardial infarction (MI), myocardial injury after noncardiac surgery (MINS), stroke, and death occur in up to 18% of surgical patients.1 Hypotension is a frequent occurrence in the postoperative period and can increase the risk of postoperative vascular complications.2 Therefore, accurate prediction of postoperative hypotension can identify patients at risk for postoperative vascular complications who would benefit from early intervention. The investigators propose a feasibility study to determine the accuracy of the hypotension prediction index (HPI) parameter of the HemoSphere monitor and Acumen IQ sensor (Edwards Lifesciences, Irvine, CA) to predict postoperative hypotension in surgical patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient ≥45 years old
- •Will undergo open colorectal, hepatobiliary, or vascular surgery;
- •Is expected to have an arterial cannula inserted intraoperatively;
- •Has an anticipated stay in PACU for at least 2 hours;
- •Able to provide written informed consent
排除标准
- •Planned admission to ICU;
- •Refusal to participate;
- •Previously enrolled in the study
结局指标
主要结局
Incidence of intraoperative hypotension
时间窗: in 12 months
Describe the incidence of hypotension defined as MAP \<65 intraoperatively.
Incidence of postoperative hypotension
时间窗: in 12 months
Describe the incidence of postoperative hypotension defined as MAP \<65 in the PACU
Hemodynamic changes with treatment of hypotension
时间窗: in 12 months
Described the changes in cardiac index with each medical treatment of a hypotensive episode.
次要结局
- Sensitivity and Specificity of HPI(in 12 months)
- Cardiovascular outcomes(in 12 months)
研究者
Stephen Yang
Assistant Professor, Department of Anesthesia, Principal Investigator
Sir Mortimer B. Davis - Jewish General Hospital