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临床试验/NCT07242339
NCT07242339尚未招募不适用

Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Plus Biceps Femoris Short Head Block in Patients Undergoing Knee Arthroscopy: A Prospective Randomized Controlled Trial

Kanuni Sultan Suleyman Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年11月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
试验地点
1
主要终点
Total Opioid Consumption (Tramadol, mg)

研究概览

简要总结

This prospective, randomized, controlled, and multicenter clinical study aims to compare the postoperative analgesic efficacy of two regional anesthesia techniques commonly used in knee arthroscopy: adductor canal block (ACB) and combined adductor canal block plus biceps femoris short head (ACB+BiFeS) block. The study will evaluate postoperative pain control, opioid consumption, adverse effects, hospital stay, and patient satisfaction. Findings will help determine the most effective and safe method for postoperative analgesia in knee arthroscopy patients.

详细描述

Knee arthroscopy is one of the most common orthopedic procedures and is frequently associated with significant postoperative pain. Effective multimodal analgesia is therefore essential to reduce opioid consumption, improve early mobilization, and enhance overall patient recovery. Among the regional anesthesia techniques, the adductor canal block (ACB) is well established as an effective motor-sparing block that provides analgesia to the medial and anterior aspects of the knee. However, patients often continue to experience posterolateral knee pain, which is not consistently relieved by ACB alone.

Recent anatomical and cadaveric studies have described the biceps femoris short head (BiFeS) block as a promising technique for targeting the posterolateral knee compartment. The BiFeS block involves deposition of local anesthetic between the short head of the biceps femoris muscle and the lateral femoral cortex at the supracondylar level. Preliminary findings suggest that this block may provide effective analgesia for the posterolateral knee without causing significant motor impairment.

This prospective, randomized, controlled, multicenter clinical trial is designed to evaluate whether the addition of the BiFeS block to standard ACB improves postoperative analgesia compared with ACB alone in patients undergoing knee arthroscopy under spinal anesthesia. The study will investigate pain scores at rest and during movement, total opioid consumption, side effects, rescue analgesic requirements, and quality of recovery. The dermatomal distribution of the blocks will be optionally assessed using cold testing.

By directly comparing ACB and combined ACB+BiFeS block under standardized perioperative conditions, this study seeks to generate high-quality evidence on the clinical utility of BiFeS as an adjunct technique. The results are expected to guide anesthesiologists in selecting optimal regional analgesia strategies for knee arthroscopy, with the potential to improve patient satisfaction, reduce opioid-related complications, and shorten hospitalization.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Double (Participant, Outcomes Assessor)

盲法说明

Participants will be blinded to group allocation. Outcome assessors recording pain scores, opioid consumption, and side effects will be blinded to the intervention. The anesthesiologists performing the blocks cannot be blinded due to the nature of the procedures.

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age ≥ 18 years
  • •ASA physical status I-III
  • •Scheduled for elective knee arthroscopy under spinal anesthesia
  • •Ability to provide written informed consent

排除标准

  • •Coagulopathy or bleeding diathesis
  • •Current use of anticoagulant therapy
  • •Known allergy or contraindication to local anesthetics used in the study
  • •History of diabetes mellitus with neuropathy or other neuropathic disorders
  • •Contraindications to regional anesthesia techniques
  • •Refusal to participate

研究组 & 干预措施

Adductor Canal Block (ACB)

Active Comparator

Participants will undergo ultrasound-guided adductor canal block at the end of surgery under spinal anesthesia.

干预措施: Adductor Canal Block (ACB) Only (Procedure)

Adductor Canal Block + Biceps Femoris Short Head Block (ACB+BiFeS)

Active Comparator

Participants will undergo both adductor canal block and biceps femoris short head block at the end of surgery under spinal anesthesia.

干预措施: biceps femoris short head block + Adductor Canal Block (ACB) (Procedure)

结局指标

主要结局

Total Opioid Consumption (Tramadol, mg)

时间窗: 24 hours

The total dose of tramadol administered via intravenous patient-controlled analgesia (PCA) device within the first 24 hours postoperatively will be recorded in milligrams.

次要结局

  • Postoperative Pain with Movement and at rest (NRS)(At 0, 6, 12, and 24 hours after surgery)
  • Rescue Analgesia Requirement(Within the first 24 hours postoperatively)
  • Incidence of Nausea and Vomiting(Within the first 24 hours postoperatively)
  • Quality of Recovery (QOR-15 score)(At 24 hours after surgery)
  • Dermatomal Spread of Block(2nd hour postoperatively)
  • Motor Blockade Incidence(Within the first 24 hours postoperatively)
  • Postoperative Pain with Movement and at rest (NRS)(At 0, 6, 12, and 24 hours after surgery)
  • Rescue Analgesia Requirement(Within the first 24 hours postoperatively)
  • Incidence of Nausea and Vomiting(Within the first 24 hours postoperatively)
  • Quality of Recovery (QOR-15 score)(At 24 hours after surgery)
  • Dermatomal Spread of Block(2nd hour postoperatively)
  • Motor Blockade Incidence(Within the first 24 hours postoperatively)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Engin Ihsan Turan

principal investigator

Kanuni Sultan Suleyman Training and Research Hospital

研究点 (1)

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