ACTRN12623000848606招募中3 期
A Prospective angiOtensin vs. noRadrenaline Trial for Hypotension management to determine the effect on length Of hospital stay in cardiac Surgery
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 400
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1. Coronary artery bypass grafting (CABG) surgery, valve repair or replacement (VR) surgery or a combination of CABG and VR surgery
- •2. Elevated risk of acute kidney injury as predicted by any of the following:
- •a) Haemoglobin <130g/l
- •b) Creatinine > 100mmol/l
- •c) Age > 70 years
- •d) New York Heart Association classification 4
- •e) Body Mass Index > 30 kg/m2
排除标准
- •1. Major aortic surgery, transplant surgery, pulmonary thrombendarterectomy or ventricular assist device surgery
- •2. Already receiving inotropic or vasopressor support
- •3. Dialysis dependent, prior renal transplant
- •4. Pre-existing significant hypertension (systolic blood pressure > 180mm Hg)
- •5. Significant pulmonary hypertension (estimated systolic pulmonary artery pressure (PAP) > 70mmHg, mean PAP > 40mmHg) AND right ventricular systolic dysfunction (graded more severe than mild)
- •6. Pregnant or breastfeeding women
研究者
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