Phase Angle as a Marker of Muscle Damage, Muscle Fatigue and Inflammation, After Eccentric Exercise
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Phase angle
研究概览
简要总结
The purpose of this study will be to assess the effectiveness of bioimpedance device (BIA) as a safe, rapid, and non-invasive method of analyzing muscle damage induced by high intensity induced eccentric exercise as an alternative measurement tool against traditional assessment methods.
A sample of 28 sedentary subjects will be recruited, all participants will perform an eccentric exercise protocol.
Measurements will be done before performing the exercise protocol, immediately after finishing the protocol, 3h after the end of the exercise protocol, 24h after the end of the exercise protocol and 48h after the end of the exercise protocol.
The variables analyzed in all subjects will be phase angle, creatinkinase, jumping strength, VAS scale, white blood count cell, quadriceps muscle thickness, Borg scale and anxiety and depression questionnaires.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy subjets
- •Sedentary subjects
排除标准
- •Trained subjects
- •Subjects with musculoskeletal pathology
- •Previous Surgeries in the last 6 months
- •Subjects under pharmacological treatment
研究组 & 干预措施
Single group: excentric exercise protocol
Excentric exercise protocol will be performed for all subjets, consisted of 10 sets of 20 repetitions of squats, jumping from a height of 50 cm
干预措施: Experimental: Single group: excentric exercise protocol (Other)
结局指标
主要结局
Phase angle
时间窗: change from baseline to 72 hours
The phase angle, which is measured via bioelectrical impedance analysis (BIA), InBody 770 ,is a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases. The phase angle was calculated automatically by the BIA device from these two components according to the following formula: phase angle (°) = (reactance/resistance) × (180°/π).
次要结局
- Creatinkinase (CK concentration)(change from baseline to 72 hours)
- cellular inflammatory markers(change from baseline to 72 hours)
- Pain: VAS(change from baseline to 72 hours)
- Quadriceps thickness(change from baseline to 72 hours)
- Leg power(change from baseline to 72 hours)