Pregnancy in the Context of Climate Change: Co-creating Climate-responsive Antenatal Care for Urban Tanzania (the CC-ANC Project).
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 1,060
- 试验地点
- 1
- 主要终点
- Rate of antepartum stillbirths (pre-hospital stillbirths).
研究概览
简要总结
Tanzania's population is growing quickly, and Dar es Salaam is one of the fastest-growing cities in the world. At the same time, the city is increasingly affected by very hot weather, flooding, and air pollution. Many parts of Dar es Salaam do not have enough roads, drainage, housing, or public services for the number of people living there. About 70% of people live in unplanned neighborhoods, often in areas that are more exposed to flooding, heat, and pollution. This means many families face greater environmental risks in their daily lives.
The health system has also struggled to keep up with the city's rapid growth. Maternity services are often overcrowded, and many women and children in urban Tanzania now face worse birth outcomes than those in rural areas. Poverty, large gaps between rich and poor, weak infrastructure, and congested hospitals all make it harder for pregnant women to get the care they need.
This makes Dar es Salaam an important place to study how antenatal care can better respond to climate-related risks and the realities of urban life.
The study is expected to provide useful lessons not only for Tanzania, but also for other countries in sub-Saharan Africa and other low- and middle-income settings. This is especially important because more than half of the world's population now lives in cities, and most future urban growth is expected to happen in Africa and Asia.
The study will evaluate whether a co-created antenatal care program can improve the quality of pregnancy care and reduce serious pregnancy problems among pregnant women receiving care in government health facilities in Temeke District, Dar es Salaam, Tanzania. The program is designed for busy urban public clinics and includes guidance for pregnant women and their families, guidance for health providers, training for providers, a booklet for women, and text messages to support antenatal care visits and health information sharing. The study will be implemented in all 21 government facilities in the district that provide antenatal care and/or gynecological and childbirth care.
The study will use a pre-post implementation comparison design. Researchers will compare pregnancy care and outcomes before the program is introduced with pregnancy care and outcomes after implementation. The primary outcome is antepartum stillbirth, meaning a baby dies before labor starts. Secondary outcomes are preterm birth and the quality of uncomplicated postabortion care. The study will also examine whether the program improves the quality of antenatal care by helping health providers better identify and manage problems in pregnancy, especially high blood pressure disorders and early pregnancy complications such as miscarriage, and by improving women's understanding of key health information, the timing of the first antenatal visit, and the number of antenatal visits attended.
Information for the evaluation will be collected from antenatal cards, case files, hospital registers, medical records, interviews, and other study activities involving pregnant women and health providers. Researchers hope the findings will show whether a locally developed antenatal care improvement program can help prevent avoidable harm to mothers and babies and improve pregnancy care in a high-volume urban setting.
详细描述
The PartoMa ANC study is a district-wide, mixed-methods implementation study designed to co-create, implement, and evaluate a context-tailored antenatal care (ANC) quality improvement intervention in Temeke District, Dar es Salaam, Tanzania. The study is grounded in the premise that pregnancy care in rapidly urbanizing, climate-vulnerable settings is shaped not only by clinical practice, but also by interacting social, environmental, and health-system constraints.
The intervention extends prior PartoMa work in childbirth care by shifting the focus upstream to ANC, with the aim of strengthening prevention, early detection, and initial management of pregnancy-related complications within routine public-sector services. The study is situated in the governmental health sector of Temeke District, which includes 21 facilities providing ANC, including facilties which also provide gynecological and childbirth care.
The scientific rationale for the study is that climate change, urbanization, and sexual and reproductive health and rights are closely interconnected, yet ANC models in low-resource urban settings rarely account for these interacting pressures. In Dar es Salaam, rapid population growth, unplanned settlement patterns, environmental hazards, and overstretched health services may contribute to poor pregnancy care experiences and adverse maternal and perinatal outcomes despite high contact with ANC services.
The protocol further builds on findings from the ongoing PartoMa studies suggesting persistent gaps in antenatal risk detection, birth preparedness, and management of untreated pregnancy complications. The present study therefore seeks to generate evidence on how a locally adapted ANC intervention can be embedded in routine care in a way that is feasible, acceptable, and responsive to the realities of a congested urban health system.
The intervention is informed by an explicit programme theory and by conceptual frameworks drawn from Complex Adaptive Systems and social practice theory. Within this framework, ANC is understood as a dynamic system in which women, families, providers, facilities, referral pathways, and wider contextual influences interact in non-linear ways. The study hypothesizes that intervention effects will arise through multiple linked mechanisms, including improved provider learning and decision-making, improved uptake and integration of ANC guidance into existing practice, and greater alignment between care content and the needs, preferences, and lived realities of pregnant women. This theory-driven approach is intended not only to assess whether the intervention works, but also to understand how and under what contextual conditions it may be implementable and scalable.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant women attending antenatal care at participating government health facilities in Temeke District, Dar es Salaam, during the study period.
- •Able and willing to provide informed consent.
排除标准
- •Women not attending antenatal care at a participating government health facility in Temeke District.
- •Women who do not provide informed consent.
- •Individuals otherwise not eligible according to local ethical requirements.
研究组 & 干预措施
The CC-ANC intervention.
This is a single-group, district-wide implementation study using a pre-post comparison design. After the baseline data collection, the CC-ANC intervention will be introduced in all 21 government health facilities in Temeke District that provide antenatal care and/or gynecological and childbirth care. There is no concurrent control group and no randomized assignment to different interventions. Study effects will be evaluated by comparing key process and clinical indicators measured before implementation with the same indicators measured after implementation under routine service conditions.
干预措施: CC-ANC intervention group. (Behavioral)
结局指标
主要结局
Rate of antepartum stillbirths (pre-hospital stillbirths).
时间窗: From enrollment to live birth.
Antepartum stillbirths are the study's primary outcome indicator. The outcome will be assessed as the rate of pre-hospital stillbirths and compared between the pre-intervention and post-intervention periods to evaluate whether the CC-ANC intervention reduces adverse pregnancy outcomes. The protocol explicitly identifies antepartum stillbirths as the primary indicator and later operationalizes this outcome as pre-hospital stillbirths for sample size estimation and analysis.
次要结局
- Preterm births.(At birth.)
- Uncomplicated postabortion care.(Until 28 weeks gestational age.)
研究者
Dan Meyrowitsch
Professor
University of Copenhagen
