NCT05749523撤回4 期
The Influence of Exercise and Hydration to the Pharmacological Response to Inhaled Terbutalin and Salbutamol in Men
Vibeke Backer1 个研究点 分布在 1 个国家开始时间: 2013年11月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Urine concentration of salbutamol and terbutalin
研究概览
简要总结
To investigate the effects of dehydration and exercise for the urine secretion of beta2-agonists.
详细描述
No studies have examined the influence of factors such as exercise and dehydration on the pharmacokinetic profile of asthmatic drugs (beta2-agonists). Exercise may modify the metabolism and excretion of drugs, and sweat loss during exercise can result in dehydration, both affecting the urine concentration of the drug.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •aerobic capacity more than 50ml / min / kg
- •more than 5h training pr week
排除标准
- •allergy for the medicine
- •chronic diseases
研究组 & 干预措施
Exercise
Other
Exercise vs. non-exercise
干预措施: Exercise (Behavioral)
结局指标
主要结局
Urine concentration of salbutamol and terbutalin
时间窗: 7 days
Urine concentration of salbutamol and terbutalin
次要结局
未报告次要终点
研究者
Vibeke Backer
Professor, Dr. Med. Chief Physician
Bispebjerg Hospital
研究点 (1)
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