ITMCTR2000004171招募中4 期
Explore the best time for ATO to treat PV combined with compound Huangdai tablets
Southern Hospital0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 性别
- All
入选标准
- •1. Aged 14–75 years, Newly diagnosed PV with t(15; 17)(q22; q12);
- •2. Pre-treatment peripheral blood white blood cell(WBC) count < 10 x 10^9/L;
- •3. Able to complete the entire treatment process;
- •4. Signed written informed consent provided by the patient or their family.
排除标准
- •1. Allergy to the drug ingredient or the supplementary material, or having an allergic constitution;
- •2. Cardiac insufficiency (cardiac contraindications: left-ventricular ejection fraction (L-VEF) < 50%));
- •3. Inadequate renal reserve (defined as total creatinine > 3 times the institutional upper limit of the normal range);
- •4. Significant arrhythmias, electrocardiogram (EKG) abnormalities (congenital long QT syndrome; history or presence of significant ventricular or atrial tachyarrhythmia; clinically significant resting bradycardia (< 50 beats per minute);
- •QTc > 450 ms on screening EKG; right bundle branch block plus left anterior hemiblock, bifascicular block);
- •5. Combined with other malignant tumors;
- •6. Pregnant and lactating women;
- •7. Participants in other drug trials in the last 3 months;
- •8. Suffering from mental illness or other circumstances which render them unable to complete the treatment plan.
研究者
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