NCT02397967已完成不适用
Neuropsychological Characterisation of Cognitive Deficits Involved in Reading Disability in Children With NF1
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 181
- 试验地点
- 12
- 主要终点
- Phonological deficits evaluated by the metaphonological capabilities including a subtraction test and phonemic Acronym test and memory capacity with phonological phonological memory test.
研究概览
简要总结
A national, multicenter, randomized, transverse clinical trial, estimating the existence of phonological deficits in children with NF1 children compared with control children without NF1 with the same reading level.
详细描述
To determine the phonological and visio -spatial performances at the NF1 children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 8 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age included between 8 and 12 years
- •Child presenting a type 1 neurofibromatosis according to 2 criteria in the following criteria list :
- •At least 6 café au lait spots
- •2 or more neurofibromas or 1 plexiform neurofibroma
- •axillary or inguinal freckling
- •1 optic nerf glioma
- •2 or more Lisch nodules
- •1 osseous lesion as sphenoid dysplasia or thinning of the long bone cortex with or without pseudoarthrosis
- •1 A first degree relative (parent, sibling, or offspring) with NF1 by the above criteria
- •Membership in a national insurance
- •Consent of the child and the parents
排除标准
- •Mental retardation (QI T < 70)
- •Treated or untreated epilepsy
- •Visual deficit (visual Acuteness < 4/10
- •Presence of a symptomatic optic glioma
- •Presence of a brain tumor.
结局指标
主要结局
Phonological deficits evaluated by the metaphonological capabilities including a subtraction test and phonemic Acronym test and memory capacity with phonological phonological memory test.
时间窗: 24 hours
Evaluate whether there is a specificity of phonological deficits in children with NF1 compared with a population of children with the same age and same reading level, taking into account the intellectual level.
次要结局
- Visual-perceptual performance established from three tests: Test of Identical Forms (Thurstone), Judgment Test of orientation Lines (Benton) and global and partial deferral Tasks (S Valdois).(24 hours)
研究者
研究点 (12)
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