Elastic Properties of the Ascending Aorta Evaluated by Imaging and Biaxial Testing
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- aortic compliance of ascending aorta (mm2/mmHg)
研究概览
简要总结
The aim of our study is to assess a correlation between local patient specific elastic modulus distribution of the ascending aorta from a biaxial tensile test and MRI measurements of the elastic properties of the aorta.
A total of 70 patients referred for ascending aorta (AA) replacement underwent a preoperative cardiac-MRI for the evaluation the elastic properties and ascending aorta tissue was collected for biaxial testing to obtain maximum elastic modulus
详细描述
Observational and prospective trial on medical data only. The patients are operated of planned aortic aneurysm without additional intervention.
The preoperative cardiac MRI are planned in standard of care.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient referred for ascending aorta aneurysm requiering replacement
- •elective patient
排除标准
- •claustrophobia
- •contraindication to performing cardiac MRI
结局指标
主要结局
aortic compliance of ascending aorta (mm2/mmHg)
时间窗: preoperative cardiac MRI performing between 1 month and 1 day before surgery
aortic compliance is a local measurement of elastic properties which is obtained with cardiac MRI images by computer processsing
次要结局
- maximum elastic modulus (MPa) of ascending aorta(biaxial testing performing between 1 and 6 hours after procedure)
研究者
MORGANT Marie-Catherine
Dr
Centre Hospitalier La Chartreuse