Video Screening for Visual Impairment of Infants
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 3,652
- 试验地点
- 1
- 主要终点
- The AUC of model based on analyzing the behavioral dynamics
研究概览
简要总结
An individual senses the world and reflects feedbacks via independent behaviors. Such precise collaboration of the sensory and behavioral systems is fundamental to survival and evolution. When a sensory modality is altered, the behavioral system has the potential to fit in a substitute modality. However, the specific dynamics of human behaviors in response to sensory loss remain largely unknown due to the paucities of representative situations and large-scale samples.
Here, the investigators focused on thousands of human infants who suffered varying degrees of visual stimuli deficiency in early stages, while their behavioral systems remained sensitive and thus retained high behavioral plasticity. Having access to this unique population provides an unprecedented opportunity to investigate the effect of diverse visual conditions on the behavioral system and develop a domestic apparatus for screening visual impariment of infants.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- — 至 4 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Younger than 4 years of age
排除标准
- •Any brain and mental illnesses, or other known illnesses that may affect the behavioral patterns
结局指标
主要结局
The AUC of model based on analyzing the behavioral dynamics
时间窗: baseline
Normal or abnormal behavioral dynamics of infants are recorded by mobile phones. Five experienced ophthalmologists identify the occurence of abnormal behaviors independently, and 2 professors with over 10 years of experience in pediatric ophthalmology department are consulted in cases of disagreement. The AUC of model based on analyzing the behavioral dynamics will be calculated.
次要结局
未报告次要终点
研究者
Haotian Lin
Principal Investigator
Sun Yat-sen University
