NCT00146926Unknown3 期
Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion
适应症
相关药物
试验速览
- 阶段
- 3 期
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- After prophylactic solution, evaluation of the pain caused by injection of propofol with a four-point scale before lose of consciousness
研究概览
简要总结
Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol
排除标准
- •sedative or analgesic drug 24h before surgery
- •allergy with drug used in the study
- •difficulty of communication
- •absence of informed written consent
结局指标
主要结局
After prophylactic solution, evaluation of the pain caused by injection of propofol with a four-point scale before lose of consciousness
次要结局
- Explicite and implicite memory of pain immediately after surgery and on day one
- Adverse effects
研究者
研究点 (1)
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