Mid- and Forefoot Disorders in Adolescents and Adults With X-linked Hypophosphatemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Number of feet with signs of osteoarthritis
研究概览
简要总结
This study aimed to characterize foot pathologies using X-rays and clinical examination and assess related outcome scores in adolescents and adults with X-linked Hypophophatemia
详细描述
A single center, cross-sectional analysis of adolescent and adult patients with XLH with and without previous surgical intervention was performed at the Orthopaedic Hospital Speising, Vienna, Austria. Clinical examination, quality of life questionnaires and radiographic data of foot x-rays in standing position were collected. Radiographic evaluation was performed to analyze foot deformity as well as signs of osteoarthritis at the foot.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 16 Years 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with confirmed XLH, ≥ 16 years were invited to participate in this study
排除标准
- •Exclusion criteria were other forms of hypophosphatemia, pregnancy and recent lower limb surgery within 3 months.
结局指标
主要结局
Number of feet with signs of osteoarthritis
时间窗: baseline
radiographic signs of osteoarthritis at the foot joints
次要结局
未报告次要终点
研究者
Forian Wenzel-Schwarz
Orthopedic surgeon
Orthopedic Hospital Vienna Speising