Retrospective Analysis of Pain in Patients Who Receive a Nerve Block for Surgery
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 166
- 主要终点
- Difference in maximum pain score, 0-10; (0 = no pain, 10 = worst pain)
研究概览
简要总结
This is a retrospective study looking at patients who received a nerve block for surgery and assessing pain after the nerve block resolves, with or without an educational intervention, over two periods of time.
详细描述
Regional anesthesia (RA) is a vital tool that can serve as the primary anesthetic or as part of a multimodal perioperative pain regimen. RA is strongly associated with decreased acute and persistent pain and opioid consumption postoperatively. However, some patients experience an acute worsening of pain into the severe range around the time of RA resolution, also known as "rebound pain" (RP). The incidence of RP has been reported as high as 40-50% after a single shot nerve block for patients undergoing ambulatory surgery.
This retrospective study aims to look at patients who received a nerve block for surgery and assessing pain after the nerve block resolves in the presence and absence of certain interventions, such as a multidisciplinary educational intervention.
The investigators will assess patients who received a primary total knee arthroplasty who received a single shot adductor canal nerve block, received pericapsular injection by the surgeon, and had a length of stay > 16 hours.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •primary total knee arthroplasty
- •received an adductor canal nerve block
- •received pericapsular injection by surgeon intraoperatively
- •admitted for overnight stay and > 16 hours post-nerve block
排除标准
- •age < 18
- •prior total knee arthroplasty on ipsilateral knee
研究组 & 干预措施
TKA with nerve block with intervention
Patients who received a single shot adductor canal nerve block prior to total knee arthroplasty surgery during March 2019-March 2020, and received an educational intervention
干预措施: Educational intervention (Other)
TKA with nerve block no intervention
Patients who received a single shot adductor canal nerve block prior to total knee arthroplasty surgery January 2017-June 2018
结局指标
主要结局
Difference in maximum pain score, 0-10; (0 = no pain, 10 = worst pain)
时间窗: 6-24 hours
Difference in maximum pain score, numerical pain rating scale 0-10, 6-24 hours after nerve block between the two cohorts
次要结局
- Difference in total opioids given(6-24 hours)
- Average pain score 0-10; (0 = no pain, 10 = worst pain)(6-24 hours)
- Difference in incidence of rebound pain(6-24 hours)
- Comparison of evening opioids given(6-24 hours)
- Difference in length of stay(0-2 years)
研究者
Yun-Yun K. Chen
Principal Investigator
Brigham and Women's Hospital