Analgesia Nociception Index for Pain Monitoring in Intensive Care Units
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 180
- 主要终点
- Analgesia Nociception Index for pain monitorization
研究概览
简要总结
The aim of this study is to examine the usability of ANI in patients who will be treated in intensive care unit.
详细描述
The aim of this study is to examine the usability of Analgesia Nociception Index in patients who will be treated in intensive care unit ( a- Cardiovascular b- surgical c- internal diseases), mechanically ventilated and lacking communication. The investigators will examine whether the positive inotropic/vasoconstrictor agents will have any effect on Analgesia Nociception Index.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Intensive Care Cardiovascular Patients Group 1 - Patients aged from 18 to 80 years, scheduled for elective isolated coronary bypass graft (CABG) for 2-4 vessel disease, without any perioperative complications, and who were postoperatively monitored via the analgesia nociception index in the cardiovascular intensive care will be included.
- •Intensive Care Internal Diseases Group 2 - Patients aged from 18 to 80 years, intubated or tracheostomized, In mechanical ventilation with Pressure-Controlled Ventilation mode, under perfusion neuromuscular blocker, Normothermic, non-cooperative and/or sedated and neuromuscular blocker
- •Intensive Care Patients (Obese) Group 3 - Post Bariatric surgery, over 40 BMI
排除标准
- •Intensive Care Cardiovascular Patients Group 1 Patients who required emergency surgery, had significant preoperative chronic pain, had autonomic nervous system anomalies and patients with rhythm will be excluded from the study.
- •Intensive Care Internal Diseases Group 2 Ramsey sedation scale under 5, cooperative, with spontaneous breathing effort and extremity movement, non sinusal cardiac rhythm
- •Intensive Care Patients (Obese) Group 3 - patients under 40 BMI
结局指标
主要结局
Analgesia Nociception Index for pain monitorization
时间窗: 3 Months
The duration between two R waves within heart rate variations (filtering the variations in respiratory cycles). A numeric measure of parasympathetic tonus will be obtained. This variation is between (pΣ) 0 and 100.
次要结局
未报告次要终点
研究者
Ali Sefik Koprulu, MD, Ass. Prof.
Ass. Prof.
İstanbul Yeni Yüzyıl Üniversitesi