Cancer Epidemiology in Seventh-day Adventists
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 96,000
- 试验地点
- 1
- 主要终点
- Incident cases of breast cancer among subjects with documented dietary habits.
研究概览
简要总结
The Adventist Health Study-2 is a long-term study, exploring the links between lifestyle, diet, and disease outcomes among Seventh-day Adventists. More than 96,000 church members from the U.S. and Canada are participating in the current study, AHS-2, conducted by researchers at the Loma Linda University School of Public Health.
详细描述
The Adventist Health Study-2 (AHS-2) is a large national cohort of 96,000 Seventh-day Adventists in the U.S. and Canada. The study is searching for associations between diet and risk of common and medium frequency cancers (breast, prostate, colorectal, lung, uterus, pancreas, melanoma of skin). This cohort is unusual in that about half are vegetarian, many eat soy at Asian levels, and many have very low or absent dairy intake while others eat normal amounts of dairy. Thus observations on these people, many of whom have contrasting dietary habits, may provide insights about diet and cancer, so supporting dietary changes that could be readily adopted by many.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Member of a Seventh-day Adventist church >30 years of age Ability to read English Live in the US or Canada
排除标准
- •Less than 30 years of age
- •Church members who did not complete the baseline questionnaire.
- •Incarcerated or institutionalized people
- •Non-English speakers
研究组 & 干预措施
Seventh-day Adventists
This is a prospective cohort study of 96,000 members of the Seventh-day Adventists Church in the United States and Canada age 30 and older at the time of enrollment who are proficient in English language.
结局指标
主要结局
Incident cases of breast cancer among subjects with documented dietary habits.
时间窗: Linkage with state cancer registries occurs periodically for 9 years, with first linkage at year 04 of study enrolment.
Incident cases of breast cancer as found by linkage with state cancer registries will allow calculation of hazard ratios comparing extreme quintiles of dietary intakes. The focus is on meats, soy, and dairy intakes.
次要结局
- Incident cases of prostate cancer among subjects with documented dietary intakes.(Linkage with state cancer registries occurs periodically for 9 years, with first linkage at year 04 of study enrolment.)