NCT00055250已完成2 期
A Randomized, Placebo-Controlled, Double-Blind Phase 2 Study of Gemcitabine Plus LY293111 Compared to Gemcitabine Plus Placebo in Patients With Locally Advanced or Metastatic Pancreatic Cancer
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- 6-month survival
研究概览
简要总结
The purpose of this study is to determine the effectiveness and side effects of LY293111 given in combination with gemcitabine in patients with pancreatic cancer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adenocarcinoma of the pancreas that is locally advanced or metastatic and not amenable to resection with curative intent
- •Tumor that can be measured by x-ray or scan
- •Adequate organ function
排除标准
- •Inability to swallow capsules
- •Documented brain metastases
- •Prior chemotherapy or biological therapy for this disease
结局指标
主要结局
6-month survival
次要结局
- Toxicity
- tumor response
- PK
研究者
研究点 (1)
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