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临床试验/NCT00935350
NCT00935350已完成2 期

Effect of Adding the Novel Fiber, PGX®,to Commonly Consumed Foods on Glycemic Response and Glycemic Index: A Practical and Effective Strategy for Reducing Post Prandial Blood Glucose Levels.

Glycemic Index Laboratories, Inc1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2006年5月最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
入组人数
10
试验地点
1
主要终点
Relative Blood glucose response of food with and without NVP

研究概览

简要总结

Reductions of postprandial glucose levels have been demonstrated previously with the addition of a novel viscous polysaccharide (NVP) to a glucose drink and standard white bread. This study explores whether these reductions are sustained when NVP is added to a range of commonly consumed foods.

详细描述

Recently, a commercial novel viscous polysaccharide (NVP)complex has been developed which is marketed in both the USA and Canada under the trade name PGX® (PolyGlycopleX) (InovoBiologic Inc, Calgary, AB, Canada). This complex consists of three viscous non starch polysaccharides which are processed using proprietary technology (EnviroSimplex®) to produce compressed granules which delays the onset of viscosity and increases palatability of the fiber when added to food. Previously, this fibre was shown to lower postprandial glucose levels in a dose responsive manner when mixed with a glucose drink and sprinkled onto a standard white bread demonstrating that the processing did not interfere with the effectiveness of the fiber. From this study the reduction in GI was calculated to be 7 units per gram of NVP when added to a solid food, however it is not known whether this relationship would be maintained when the NVP was added to a range of commonly eaten foods. This study therefore evaluates the effect of the addition or incorporation of NVP into a range of foods on postprandial glycemia and whether the reductions in glycemic index could be predicted using.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • healthy individuals
  • 18-75 years old
  • BMI less than 35 kg/m2

排除标准

  • Medications influencing gastrointestinal function
  • Pregnancy

结局指标

主要结局

Relative Blood glucose response of food with and without NVP

时间窗: Acute blood glucose response measured at 0, 15,30,45,60,90 and 120 min

次要结局

未报告次要终点

研究者

申办方类型
Industry

研究点 (1)

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