跳至主要内容
临床试验/NCT04075162
NCT04075162招募中不适用

Community Benefit of No-charge Calcium Score Screening Program

University Hospitals Cleveland Medical Center1 个研究点 分布在 1 个国家目标入组 77,000 人开始时间: 2014年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
77,000
试验地点
1
主要终点
Statin Prescription

研究概览

简要总结

Current approaches in primary prevention for cardiovascular disease are based on probabilistic approaches to estimate risk, using many of the widely available cardiovascular risks scores, with over 100 such scoring systems currently available throughout the world. The rationale for this practice is to select those individuals at greatest risk for more intense targets, reduce risk of treatment to those at minimal risk, and to maximize the cost-effectiveness of treatment. A recent Cochrane Systematic Review assessed the practice of using risk scores to select individuals for the primary prevention of cardiovascular disease. 3 The principal finding of the systematic review was that there was little or no effect of providing clinicians with cardiovascular risk scores when compared to standard of care (5.4% versus 5.3%; relative risk 1.01, 95% confidence intervals 0.95 to 1.08). The authors concluded that there is major uncertainty whether current strategies for providing risk scores and called for further research to address this concern. Extent of coronary artery calcium (CAC) is a strong risk marker for coronary events, with evidence mainly derived from observational studies and from prospective non-randomized studies. CAC, although endorsed for intermediate risk patients, is not widely adopted due to barriers in reimbursement. The cost of the test ranges between 100 and 300 USD in the United States, which may have limited the wide adoption of the test. Whether reducing the cost burden for CAC increases utilization for routine screening and its influence on physician practices and downstream testing is largely unknown. University Hospitals started offering low charge CAC (99$) since 2014. In 2017, University Hospitals started offering CAC for no charge for patients to improve access to this test, which has not traditionally been covered by insurance companies. The impact of no-charge CAC has never been studied.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Received Coronary Artery Calcium (CAC) CT scan at University Hospitals starting in January 1, 2014.

排除标准

  • 未提供

结局指标

主要结局

Statin Prescription

时间窗: 1 year

次要结局

  • Invasive coronary ischemia testing(1 year)
  • Non-invasive coronary ischemia testing(1 year)
  • Coronary revascularization procedures(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sanjay Rajagopalan

Division Chief of Cardiovascular Medicine

University Hospitals Cleveland Medical Center

研究点 (1)

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