Comparative evaluation of effects of Advanced-PRF (A-PRF) and A-PRF incorporated with Ascorbic Acid on Gingival Thickness during Periodontal Pocket Therapy in patients with Thin Gingival Biotype: A Randomized Clinical Control Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- gingival thickness, pocket probing depth
研究概览
简要总结
| Periodontitis is an infectious disease that culminates in inflammation within the soft tissues surrounding the teeth causing progressive bone loss. Periodontal surgery as part of the treatment of periodontal disease is mainly performed: |
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To gain access to diseased areas for adequate cleaning;
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To achieve pocket reduction or elimination; and
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To restore the periodontal tissues lost through the disease; i.e., a new attachment formation or periodontal regeneration.
To accomplish this goal of periodontal therapy, a number of surgical procedures have been advocated throughout the years.
Surgical debridement is a common procedure for teeth with deep periodontal pockets and horizontal bone loss. Surgical debridement with flap repositioning may often result in gingival recession which is seen due to lack of bone support for the flap, thin gingival tissue with limited blood supply and shrinkage of flap.
The gingival thickness is a significant predictor of clinical outcome of periodontal surgeries. A thick gingival biotype is a requisite for good periodontal health. It has important role in resisting trauma and subsequent gingival recession.
The term "gingival biotype" refers to the morphological characteristics of the gingiva and the tooth, whereas the terms "periodontal biotype," "periodontal morphotype," "gingival morphotype," and "gingival phenotype" refer to the clinical variations in the gingival thickness (GT) and keratinized tissue width (KTW), as well as other characteristics, such as bone morphotypes, tooth shape, and, morphological characteristics of the gingiva and the periodontium
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 55.00 Year(s)(—)
- 性别
- All
入选标准
- •Adult male and female patients in age group of 20-55 years 2.Pocket probing depth more than 5mm in anterior Teeth 3.Gingival thickness less than 1mm 4.Horizontal bone loss.
排除标准
- •1.Pregnancy and lactation 2.Smokers and tobacco users 3.Hypertension 4.Diabetes 5.Other systemic disorders 6.Vertical/angular bone loss 7.Grade 2 mobile teeth 8.Patients who are unwilling to participate in the study.
结局指标
主要结局
gingival thickness, pocket probing depth
时间窗: baseline, 3 months , 6 months
次要结局
- recession depth, keratinized tissue width, relative attachment level, plaque index, gingival index(baseline, 3 months, 6 months)
研究者
Dr Diksha Aswekar
Goa Dental College and Hospital Bambolim
