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临床试验/NCT07333404
NCT07333404已完成不适用

The Effects of Combined Transcranial Direct Current Stimulation and Pneumatic Compression on Selected Recovery Parameters After a 10K Run

Uludag University2 个研究点 分布在 1 个国家目标入组 16 人开始时间: 2026年1月5日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
16
试验地点
2
主要终点
Cognitive Performance: Stroop Test

研究概览

简要总结

This study will examine how two recovery methods-pneumatic compression (PC) applied to the legs and transcranial direct current stimulation (tDCS) applied to the head-help athletes recover after a 10-kilometer (10K) run. It also aims to find out which methods may help master athletes recover faster, maintain performance, and reduce the risk of injury.

Men aged 40-55 who are trained long-distance runners can participate, provided they do not have medical conditions that prevent safe exercise or use of the recovery methods. Participants will run 10K and then receive one of the following interventions in a randomized order: tDCS, PC, tDCS + PC, or no intervention (control). Each participant will experience all conditions, with a one-week break between sessions. Measurements will be taken before the run, immediately after, and after the intervention, including heart rate variability, cognitive tests (Stroop Test), vertical jump, and maximal voluntary muscle contraction, during which muscle activity will be recorded using electromyography (EMG). Data will be analyzed to compare how each intervention affects recovery, including physical performance, cognitive function, and psychological state.

The study will show which methods help master runners recover faster and more effectively, provide practical strategies to improve performance and reduce injury risk, and offer information on the separate and combined effects of tDCS and PC on recovery, which could help design age-specific recovery strategies for endurance athletes.

详细描述

The aim of this study is to investigate the effects of combined transcranial direct current stimulation (tDCS) and pneumatic compression (PC) on recovery in master male runners following a 10-kilometer run. The study also aims to examine whether these interventions can shorten recovery time and prevent performance decline after prolonged and intense exercise.

This study will be conducted as a randomized, controlled, crossover trial using a mixed experimental design. Each participant will undergo four different recovery protocols in a randomized order, with a one-week interval between sessions. Randomization will be performed using Research Randomizer, assigning participants to one of four sequences (e.g., B-A-D-C). Participants will be identified only by numerical codes to ensure blinding and maintain confidentiality. Each participant will experience all protocols, allowing within-subject comparisons and minimizing order-related bias.

The four recovery protocols are:

(A) tDCS group: transcranial direct current stimulation only (B) PC group: pneumatic compression (PC) only (C) tDCS + PC group: simultaneous application of both tDCS and PC (D) Control group: passive rest with no intervention

The tDCS and PC interventions represent the independent variables, while dependent variables include the Well-being Questionnaire (WBQ), Total Quality Recovery (TQR), heart rate variability (HRV), Stroop Test performance, vertical jump height, and maximal voluntary isometric contraction (MVIC) with electromyography (EMG) recordings.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
40 Years 至 55 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Age 40 to 55 years
  • Completion of an official 10-kilometer race in under 50 minutes within the last six months
  • Regular training 5 days per week, 90 minutes per day
  • Weekly running volume of 60-80 kilometers
  • Aerobic fitness ≥ 80% according to American College of Sports Medicine (ACSM) guidelines

排除标准

  • Use of regular medications within the last six months
  • Consumption of stimulants, caffeine, or alcohol within 24 hours prior to testing
  • Musculoskeletal injuries within the last six months
  • Participation in current physical therapy programs
  • Epilepsy or history of seizures
  • Cardiac, brain, or other electronic implants
  • Open wounds or dermatological conditions on the head
  • Circulatory disorders, including deep vein thrombosis, peripheral arterial disease, or severe varicose veins
  • Previous exposure to transcranial direct current stimulation (tDCS) or pneumatic compression (PC) interventions

研究组 & 干预措施

tDCS

Experimental

20 minutes of transcranial direct current stimulation (tDCS) applied to the F3 and F4 regions of the brain using the Brain Premier device at 2 mA intensity.

干预措施: Transcranial Direct Current Stimulation (tDCS) (Device)

Pneumatic Compression (PC)

Experimental

20 minutes of sequential pneumatic compression (PC) applied to the lower limbs using the Normatec device, with compression pressure adjustable between 20 to 100 mmHg.

干预措施: Normatec Pneumatic Compression (Device)

tDCS + PC

Experimental

Participants will receive simultaneous application of transcranial direct current stimulation (tDCS) to the F3 and F4 regions and pneumatic compression (PC) to the lower limbs for 20 minutes, combining both interventions.

干预措施: Transcranial Direct Current Stimulation (tDCS) (Device)

tDCS + PC

Experimental

Participants will receive simultaneous application of transcranial direct current stimulation (tDCS) to the F3 and F4 regions and pneumatic compression (PC) to the lower limbs for 20 minutes, combining both interventions.

干预措施: Normatec Pneumatic Compression (Device)

Control

No Intervention

20 minutes of passive rest in a semi-reclined position, no intervention applied.

结局指标

主要结局

Cognitive Performance: Stroop Test

时间窗: Immediately before 10K run, immediately after 10K run, immediately after recovery intervention

Cognitive performance will be assessed using the computerized Stroop Test. Participants will respond to color-word stimuli where the color of the word may be congruent or incongruent with the written word. Reaction time and accuracy will be recorded to evaluate cognitive function and executive control in response to exercise and recovery interventions.

Maximal Voluntary Isometric Contraction (MVIC)

时间窗: Assessments will be performed immediately before the 10-kilometer run, immediately after completion of the 10-kilometer run, and immediately after the recovery intervention.

Maximal voluntary isometric contraction (MVIC) of the quadriceps muscles (vastus lateralis, rectus femoris, and vastus medialis) will be measured using surface electromyography (EMG) to assess neuromuscular function and fatigue. Participants will perform three contractions lasting 3 to 5 seconds each, with 60-second rest intervals, while seated with the knee and hip joints positioned at 90 degrees.

Heart Rate Variability (HRV)

时间窗: Immediately before 10K run, immediately after 10K run, immediately after recovery intervention

Heart rate variability will be measured using the Polar Vantage V3 GPS watch with H10 heart rate sensor to assess autonomic nervous system responses to exercise and recovery interventions. HRV parameters will be analyzed to evaluate physiological stress and recovery. Measurements will be recorded at rest for 5 minutes in a seated position.

Cognitive Performance: Stroop Test

时间窗: Immediately before 10K run, immediately after 10K run, immediately after recovery intervention

Cognitive performance will be assessed using the computerized Stroop Test. Participants will respond to color-word stimuli where the color of the word may be congruent or incongruent with the written word. Reaction time and accuracy will be recorded to evaluate cognitive function and executive control in response to exercise and recovery interventions.

次要结局

  • Total Quality Recovery (TQR)(Immediately before the 10-kilometer run (T1), immediately after the 10-kilometer run (T2), and immediately after the recovery intervention (T3).)
  • Total Quality Recovery (TQR)(Immediately before the 10-kilometer run (T1), immediately after the 10-kilometer run (T2), and immediately after the recovery intervention (T3).)
  • Well-Being Questionnaire (WBQ)(Immediately before the 10-kilometer run (T1), immediately after the 10-kilometer run (T2), and immediately after the recovery intervention (T3).)
  • Vertical Jump(Immediately before 10K run, immediately after 10K run, immediately after recovery intervention)

研究者

发起方
Uludag University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ramiz ARABACI

Professor

Uludag University

研究点 (2)

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