NCT01012856Unknown2 期
Explicit and Implicit Change of Depression in Exposure-based Cognitive Therapy
适应症
试验速览
- 阶段
- 2 期
- 入组人数
- 142
- 试验地点
- 2
- 主要终点
- severity of depressive symptoms measured by the Beck-Depression-Inventory (BDI-II)
研究概览
简要总结
The purpose of this study is to investigate, if exposure-based cognitive therapy (EBCT) is at least as effective as the established cognitive-behavioral therapy and more effective in its long-term efficacy. Moreover the mechanisms of change of the EBCT are investigated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major Depressive Disorder according to DSM-IV as main diagnosis
- •minimum standardized depression scores (BDI >= 17; HAMD >=13)
- •minimum age of 18 years
- •informed consent to participate voluntarily in the study
- •sufficient German language skills
排除标准
- •acute suicidality
- •depressive disorder with mood-incongruent psychotic features
- •chronic depressive disorder
- •organic cause of depression
- •drug-induced depression
- •bipolar disorder
- •diagnosis of schizophrenia, schizophreniform, schizoaffective disorders, and/or psychosis NOS
- •comorbid dysthymia, psychotic disorder (acute or anamnestic), dementia, substance dependence, schizotypal/ borderline/ or antisocial personality disorder
- •psychopharmacological treatment other than antidepressants
- •antidepressant medication, if it is changed within one month prior to the beginning of psychotherapy
- •other simultaneous psychological treatments
结局指标
主要结局
severity of depressive symptoms measured by the Beck-Depression-Inventory (BDI-II)
时间窗: end of therapy, 6 month after end of therapy (follow up)
次要结局
- symptom impairment measured by the Brief Symptom Inventory (BSI)(end of therapy, 6-month follow up)
- quality of life measured by the WHO Quality of Life-BREF (WHOQOL-BREF)(end of therapy, 6-month follow-up)
- interpersonal problems measured by the Inventory of Interpersonal Problems (IIP)(end of therapy, 6-month follow-up)
- avoidance measured by the Cognitive-Behavioral Avoidance Scales (CBAS)(end of therapy, 6-month follow-up)
- resources measured by the Bernese Inventory of Resources (RES-K)(end of therapy, 6-month follow-up)
- explicit self-esteem measured by the Rosenberg self-esteem scale (RSES)(end of therapy, 6-month follow up)
- implicit self-esteem measured by the Self-Esteem Implicit Association Test (SE-IAT)(end of therapy)
- goal attainment measured by Goal Attainment Scaling (GAS)(end of therapy)
- avoidance motivation measured by the Inventory of Approach and Avoidance Motivation (IAAM)(end of therpy, 6-month follow-up)
- motivational incongruence measured by The Incongruence Questionnaire (INC)(end of therapy, 6-month follow-up)
研究者
研究点 (2)
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