ACTRN12615000522516尚未招募2 期
A prospective, randomised study of seriously injured, shocked adult trauma patients in an urban setting, comparing resuscitation outcomes following administration of an intravenous hemoglobin-based oxygen carrier-201 (HBOC 201) to Normal Saline.
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 110
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 55 Years（—）
- 性别
- All
入选标准
- •1) Age 18 to less than 55 years
- •2) Injury with obvious/suspected haemorrhagic shock
- •3) Pre-hospital Shock Index >=1.0
- •4) Road transport by MICA paramedic to either The Alfred or the Royal Melbourne Hospitals
- •5) External haemorrhage control attempted in patients with external bleeding
- •6) IV access secured
排除标准
- •1) Penetrating Traumatic Brain Injury
- •2) Paralysis (not as a result of paralysing agent administration).
- •3) Pregnancy—known or suspected by next of kin if at scene
- •4) Cardiac arrest (an absence of spontaneous circulation)
- •5) Known allergy to HBOC-201
- •6) Known opposition to HBOC-201 administration
- •7) Burn > 20% body surface area (BSA) (partial or full thickness)
- •8) Blood for transfusion available at scene
研究者
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