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临床试验/CTRI/2025/05/087283
CTRI/2025/05/087283已完成不适用

To assess the effect of early enteral feeding VS delayed enteral Feeding in mild and moderate acute pancreatitis patients in a tertiary care hospital in puducherry

Jayastip1 个研究点 分布在 1 个国家目标入组 88 人开始时间: 2025年5月30日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
88
试验地点
1
主要终点
To assess the effect of early vs delayed enteral feeding in mild and moderate acute pancreatitis

研究概览

简要总结

The study is plan to conducted in IGMC&RI in the department of General medicine among mild and moderate acute pancreatitis based on Balthazar CT severity index the patients were divided by simple randomization into 2 groups as  A & B. Group A receives early enteral feeding ( within 24 hours) and Group B receives delayed enteral feeding ( after 48 hours ). SOFA and BUN/Albumin ratio will be measured in both the groups at the time of admission, Enteral nutrition: 25- 30 Kcal / kg/ day , 200 – 300 ml, 5-6 times /day, Intermittent bolus Feeds were commenced at full strength and a rate of 30 ml/h increasing to 100 ml/h over 24–48 h. SOFA score and BUN/Albumin ratio will be measured in both the groups after 4 days of admission . Assess the effect of early vs delayed  enteral nutrition in view of reducing the systemic/local complication, organ failure and length of hospital stay.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Age more than or equal to 20 years including both the sexes who are diagnosed as mild and moderate pancreatitis based on Balthazar CT severity index ( score less than 7) at the time of admission.

排除标准

  • Age less than 20 years chronic pancreatitis severe acute pancreatitis based on Balthazar CT severity index ( score more than 7) pancreatic cancer shock at the time of presentation (systolic BP less than 90 mm hg) Patients with co-morbidities like COPD, Renal impairment Pregnant women patient with known history of allergy to iodinated contrast agents All patients who will not give consent for study.

结局指标

主要结局

To assess the effect of early vs delayed enteral feeding in mild and moderate acute pancreatitis

时间窗: Day 1 and day 4

次要结局

  • To assess the BUN/albumin ratio as severity predictors in acute pancreatitis.(Day 4)

研究者

发起方
Jayastip
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Jayasti.P

Indira Gandhi medical College and research institute , Kathirkamam, puducherry

研究点 (1)

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