Clinical Comparison of Topical Application of Alvogyl Versus Topical Application of Hyaluronic-Acid Gel in Management of Pain And Palatal Wound Healing : A Randomized Controlled Clinical Trial
试验速览
- 阶段
- 1 期
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- postoperative pain
研究概览
简要总结
The aim of the study is to evaluate the effect of application of Alvogyl versus hyaluronic acid in decreasing postoperative pain and promoting healing in the palatal wound following the free gingival graft procedure
详细描述
Postoperative pain and bleeding are the most common complications after palatal graft harvesting, also postsurgical swelling have been reported. Although hemostatic agents, mechanical barriers, bioactive materials, antibacterial and antiseptic agents and herbal products have been found effective in preventing such complications, an ideal support could not be specified for this purpose. Further, undesired side effects such as delayed wound healing/foreign body reaction have been reported .
No gold standard has been identified, thus there is a need for further investigations aiming to reach the best possible treatment modality for pain relief and prevention of reported complications following harvesting of palatal graft .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with mucogingival defects scheduled for free gingival graft
- •Age from 18 years up to 60
- •Medically healthy patient
排除标准
- •Systemic diseases that may be a contraindication for any surgeries.
- •Loss of maxillary premolars and molars.
- •Pregnancy or lactation
结局指标
主要结局
postoperative pain
时间窗: 7th days
Pain through one week using the visual analogue scale (VAS)
次要结局
- Wound healing(7th, 14th, 21st and 30th days.)
研究者
mohy eldin mahmoud aboelazayem
Principal Investigator
Cairo University