ISRCTN60187959已完成不适用
Effects of non-surgical periodontal therapy on periodontal laboratory and clinical data as well as on disease activity in patients with rheumathoid arthritis
niversity of Medicine and Pharmacy Cluj-Napoca0 个研究点目标入组 36 人开始时间: 2016年11月24日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Moderate or severe chronic periodontitis; >30 years of age
- •2. =10 natural teeth present in the oral cavity
- •3. Full-mouth plaque scores (FMPS) =30% after oral hygiene instructions
- •4. No other systemic diseases or medications except for RA, which are known to influence periodontal conditions/treatment outcome (e.g. Down Syndrome, HIV, Diabetes Mellitus type 1 and 2)
- •5. DAS28=3.2
- •6. No infectious or heart diseases that need prophylactic administration of antibiotics before dental treatment
- •7. No liver disease; no head and neck radiation therapy
排除标准
- •1. Non-surgical periodontal therapy within the previous 12 months
- •2. Systemic or local use of antibiotics within the previous 3 months
- •3. Medication with a possible influence on the periodontium (e.g., ciclosporines, phenytoines, calcium channel blockers)
- •4. Pregnancy or lactation
- •In the RA group, RA was diagnosed according to the criteria set by the American College of Rheumatology;
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