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临床试验/ISRCTN60187959
ISRCTN60187959已完成不适用

Effects of non-surgical periodontal therapy on periodontal laboratory and clinical data as well as on disease activity in patients with rheumathoid arthritis

niversity of Medicine and Pharmacy Cluj-Napoca0 个研究点目标入组 36 人开始时间: 2016年11月24日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
36

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Moderate or severe chronic periodontitis; >30 years of age
  • 2. =10 natural teeth present in the oral cavity
  • 3. Full-mouth plaque scores (FMPS) =30% after oral hygiene instructions
  • 4. No other systemic diseases or medications except for RA, which are known to influence periodontal conditions/treatment outcome (e.g. Down Syndrome, HIV, Diabetes Mellitus type 1 and 2)
  • 5. DAS28=3.2
  • 6. No infectious or heart diseases that need prophylactic administration of antibiotics before dental treatment
  • 7. No liver disease; no head and neck radiation therapy

排除标准

  • 1. Non-surgical periodontal therapy within the previous 12 months
  • 2. Systemic or local use of antibiotics within the previous 3 months
  • 3. Medication with a possible influence on the periodontium (e.g., ciclosporines, phenytoines, calcium channel blockers)
  • 4. Pregnancy or lactation
  • In the RA group, RA was diagnosed according to the criteria set by the American College of Rheumatology;

研究者

发起方
niversity of Medicine and Pharmacy Cluj-Napoca

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