Use of Intra-Operative Shear Wave Ultrasound Vibrometry for Characterization of Esophageal Malignant Tumors
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- Mayo Clinic
- 入组人数
- 3
- 试验地点
- 2
- 主要终点
- Determining malignant esophageal tissue from normal tissue
研究概览
简要总结
Using the analysis of group velocity for a screening application and then higher order analysis based on the elastic and viscious components of the shear modulus may allow discrimination between extent of tumor invasion through the esophageal wall if appropriately correlated with pathological findings.
详细描述
Use of ultrasound-based vibrometry in this setting would allow for a relatively simple study and translation of clinical practice, as the same devices are already used in this setting, and operators have familiarity with the equipment. Incorporating another additional method to generate contrast for determining malignant tissue from normal based on biomechanical properties with the same probe would have benefit as an additional diagnostic modality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Device Feasibility
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 18 years old
- •Scheduled to undergo esophageal reconstruction for presumed or known esophageal cancer
- •Subject is able to understand the study procedures and provide informed consent.
排除标准
- •Subject is pregnant or breast feeding.
研究组 & 干预措施
Ultrasound
干预措施: General Electric LOGIQ E9 ultrasound system (Device)
结局指标
主要结局
Determining malignant esophageal tissue from normal tissue
时间窗: 1 week
Determining malignant esophageal tissue from normal tissue by measurements using the General Electric LOGIQ E9 ultrasound system.
次要结局
未报告次要终点