ACTRN12617000561381招募中未知
Gastrointestinal eradication of multi-resistant gram negative bacteria by faecal microbiota transplantation (FMT)
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 22
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 85 Years（—）
- 性别
- All
入选标准
- •1. Patients with refractory or recurrent infection–defined as at least 3 episodes of infection requiring at least 3 episodes of antibiotic therapy in preceding 24 months.
- •2. These infections were caused by a Gram negative bacterium which has acquired clinically important antibiotic resistance. This is defined as reported resistance to one or more of the following antibiotics: meropenem, ceftriaxone, cefepime, ceftazidime, cefalexin, amoxicillin-clavulanate, piperacillin-tazobactam, ciprofloxacin, gentamicin or trimethoprim.
排除标准
- •1. Active gastrointestinal infection
- •Ie bacterial or viral infection causing symptoms of diarrhoea
- •(colonisation with MRGNB is not considered to be an infection)
- •2. Pregnancy
- •3. Current use of antibiotics*
- •4. Cognitive impairment
- •5. Perianal inflammation
- •6. Life expectancy < 1 year
- •7. Neutropaenia <0.5 X109/L
- •8. Severe IgE mediated food allergy : urticaria or anaphylaxis
- •9. At risk of peritonitis: including patients with ascities or peritoneal dialysis
- •*The use of trimethoprim-sulfamethoxazole is allowed when used for prophylaxis against Pneumocystis infection in immunosuppressed individuals.
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